IndraLab

Statements

USP14 inhibits PRKN. 4 / 4
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"USP14 inhibition enhances Parkin-independent mitophagy in iNeurons."
39486496
reach
"USP8, USP14, USP15, USP30, USP33, and USP35 have been shown to antagonize Parkin activity [[92], [93], [94], [95], [96], [97]]."
38295575
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"Here, we report that genetic and pharmacological inhibition of USP14 promotes mitophagy, which occurs in the absence of the well characterised mediators of mitophagy, PINK1 and Parkin."
30249595
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"45 USP14 inhibition, both genetically and pharmacologically, promotes mitophagy in the absence of PINK1 and PARKIN, two well‐known mediators of mitophagy."
35924961