IndraLab

Statements

USP1 inhibits FANCD2. 3 / 5
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"Depletion of Usp1 decreases epidermal proliferation in Fancd2 (+/-) mice."
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"However, in FA pathway, disruption of USP1 gene causes accumulation of the monoubiquitinated forms of FANCD2 and FANCI but increases ICL hypersensitivity and genomic instability [XREF_BIBR, XREF_BIBR]."
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"However, in FA pathway, disruption of USP1 gene causes accumulation of the monoubiquitinated forms of FANCD2/FANCI but increases ICL hypersensitivity and genomic instability [49, 77] ."
27398234