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USP8 increases the amount of PIK3CB. 2 / 2

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"USP8 knockdown significantly decreased PIK3CB protein expression, and this effect was abolished by PTK7 overexpression (Figure 7a), confirming that USP8 regulated PTK7 to mediate PIK3CB expression."

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"USP8 positively regulated PIK3CB expression by PTK7, thus activating PI3K/AKT pathway."

39552193

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IndraLab

Statements

USP8 increases the amount of PIK3CB. 2 / 2

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