IndraLab

Statements


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"A high affinity peptide blocker for these Ca channels is the scorpion toxin kurtoxin which inhibits the Ca (v) 3.1 and Ca (v) 3.2, but not the Ca (v) 3.3 channel in nanomolar concentrations."

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"Many of these risk genes encode proteins involved in calcium signaling including CACNA1C, CACNB2, and CACNA1I that may ultimately converge on a common disease mechanism XREF_BIBR, XREF_BIBR."

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"There is evidence that a single copy of Chr22 :39665939 G> A CACNA1I triggers calcium channel disorder and is associated with the pathogenesis of SCZ [XREF_BIBR]."