IndraLab

Statements


OTUB1 activates TNFSF12. 2 / 2
| 1 1

eidos
"Further , downregulation of ubiquitin thioesterase OTU domain ubiquitin aldehyde binding 1 ( OTUB1 ) enhances the degradation of cIAP1 and inhibits the TNF-related weak inducer of apoptosis ( TWEAK ) - induced MAPK and NF-kappaB pathway [ 33 ] ."

reach
"Downregulation of OTUB1 promotes TWEAK- and IAP antagonist stimulated caspase activation and cell death, and enhances c-IAP1 degradation."