IndraLab

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USP25 increases the amount of NANOG. 3 / 3
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"Overexpression of USP21, but not the catalytically inactive mutant C221A, led to increased Nanog levels in a dose dependent way (XREF_FIG), suggesting that USP21 upregulation of Nanog expression is dependent on DUB enzyme activity."
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"Through the screen, we found that USP21 significantly upregulated Nanog levels, whereas other DUBs had little to no effect on the Nanog expression levels (XREF_FIG)."
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"Through the screen they also found that USP21 significantly upregulated Nanog levels while other DUBs had little to no effect on the Nanog expression levels."
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