IndraLab

Statements

RPN13 inhibits UCHL5. 3 / 3
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"RPN13 disrupts a UCH37 dimer at high concentration."
25702872
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"Using a combination of mutagenesis, biochemical, and small-angle X-ray scattering (SAXS) techniques, we demonstrated that Rpn13 activated the auto-inhibited Uch37 by de-oligomerizing it and sequestering it to form a 1:1 stoichiometric complex."
24752541
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"The deubiquitinating enzyme UCH-L5 can be inhibited and activated by regulatory proteins INO80G and RPN13, respectively."
27718275