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COPS5 bound to E2F1 activates E2F1. 2 / 2

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"We previously showed that the E2F1 binding partner Jab1 and CSN5 promotes E2F1 dependent induction of apoptosis but not proliferation."

21937878

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"In addition, CSN5 specifically interacts with transcription factor E2F1 and enhances E2F1 dependent apoptosis by a mechanism that is independent of deneddylation activity [39]."

18926707

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IndraLab

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COPS5 bound to E2F1 activates E2F1. 2 / 2

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