IndraLab

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MTOR activates BAP1. 1 / 1

| 1

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"BAP1 isoform lacking part of the catalytic domain sensitized MPM cells to the PARP1 inhibitor, olaparid, and this sensitivity could be augmented by concomitant treatment with apitolisib (GDC-0980), a dual inhibitor of class 1 PI3K, and mTOR kinase, which downregulates BRCA-1."

| PMC

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IndraLab

Statements

MTOR activates BAP1. 1 / 1

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