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4-[(1R)-1-aminoethyl]-N-pyridin-4-yl-1-cyclohexanecarboxamide inhibits ATXN3. 2 / 2

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"We found that the anti-aggregation effect of ROCK inhibitors was not limited to the mutant htt and AR and that Y-27632 was also able to reduce the aggregation of ataxin-3 and atrophin-1 with expanded polyQ."

19278999

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"Y-27632, an inhibitor of Rho kinases, also decreased soluble and insoluble expanded ATXN3 in cells."

22133674

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IndraLab

Statements

4-[(1R)-1-aminoethyl]-N-pyridin-4-yl-1-cyclohexanecarboxamide inhibits ATXN3. 2 / 2

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