IndraLab

Statements


Mutated BAP1 inhibits NFkappaB. 3 / 3
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"BAP1 mutations may inhibit the NF-kappaB signaling pathway, repressing the cytokine secretion and antigen presentation by macrophages, which induces the immunosuppressive microenvironment, enhances the malignant phenotypes of UM cells and ultimately promotes the growth and metastasis of UM."

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"BAP1 mutations inhibited the NF-kappaB signaling pathway, suppressing the cytokine secretion and antigen presentation by macrophages."

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"BAP1 mutations inhibit the NF-kappaB signaling pathway to induce an immunosuppressive microenvironment in uveal melanoma."