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PKM2/PI3K/AKT increases the amount of OTUB2. 2 / 2

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"Overexpression of OTUB2 could promote glycolysis and induce proliferation, migration, and invasion of EC cells, while inhibition of the PKM2/PI3K/AKT signaling pathway significantly reversed the oncogenic effects of OTUB2 overexpression on EC cells [15]."

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"Importantly, inhibition of the PKM2/PI3K/AKT signaling pathway significantly reversed the promoting effect of OTUB2 overexpression on EC."

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IndraLab

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PKM2/PI3K/AKT increases the amount of OTUB2. 2 / 2

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