IndraLab

Statements



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"It was also found that USP4 inhibited NF-kappaB activation, but in this study we confirmed that USP4 positively regulates the NF-kappaB signalling pathway during EV71 infection."

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"The hypothesis that drove this study was that USP4 might also mediate the TGF-beta signal transduction pathway in hypertrophic scar fibroblasts."

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"As shown in previous studies [XREF_BIBR], USP4 is an effective inducer of TGF-beta signal transduction, which interacts directly with TGF-betaR1 and acts as a de-ubiquitinase enzyme to maintain the level of TGF-betaR1 on the plasma membrane."