IndraLab

Statements


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"The half-maximal inhibition for BK channel block by ketamine was increased from 4.1 +/- 0.7 microM at 0.1 microM intracellular Ca2+ to 230 +/- 74 microM at 100 microM intracellular Ca2+."

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"Also, the intravenous anesthetic ketamine (at clinically relevant concentrations : 2-500micromol/L) selectively blocks the BK channel in a dose dependent manner."