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Statements


OTUD3 activates CRC. 4 / 4
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"Therefore, we postulated that OTUD3 promotes CRC progression by up-regulating YY1."

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"Conversely, depletion of endogenous YY1 suppressed the OTUD3-induced CRC proliferation (Fig. 4C)."

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"Our findings suggest that OTUD3 promotes CRC progression by up-regulating YY1, and provides insights into the underlying mechanisms of YY1 over-expression in CRC."

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"OTUD3 accelerates CRC progression by up-regulating YY1."