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USP8 increases the amount of CDH2. 2 / 2
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"Overexpression of USP8 also increased the expression and activity of MMP9, MMP2, and N-cadherin, while it decreased the expression of TIMP-1, TIMP-2, and E-cadherin ( Fig. 2 G)."
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"Our findings indicate that the upregulation of USP8 may mediate the message recognition, migration, and invasion of trophoblast cells by regulating the expression of E-cadherin, N-cadherin, MMPs, and [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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