IndraLab

Statements


USP25 increases the amount of BRCA2. 2 / 2
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"USP21 knockdown with two independent shRNAs caused a reduction in BRCA2 protein levels that was particularly pronounced in the presence of the topoisomerase I inhibitor camptothecin (CPT), which causes DSB induction in HR-permissive S phase cells 36."

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"USP21 loss causes a decrease in BRCA2 protein levels."