IndraLab

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UCHL1 activates HIF1A. 3 / 4
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"UCHL1 increases the stability of HIF-1alpha."

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"XREF_BIBR, XREF_BIBR Work from the field of oncological science indicated UCHL1 might prevent HIF-1alpha degradation."

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"In 2D monolayer culture, a UCHL1 inhibitor suppressed HIF activity and decreased the transcription of HIF downstream genes by inhibiting the UCHL1 mediated accumulation of HIF-1alpha."