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BAP1 activates SNAI1. 2 / 2

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"Furthermore, BAP1 knockout in clear cell renal cell carcinoma (ccRCC) inhibits cell growth and migration and promotes the mesenchymal-epithelial transition (MET) partially by downregulating Snail and reducing Rho family GTPases activity [40]."

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"Loss of BAP1 has been reported to downregulate the expression of Snail , promoting ccRCC cells towards mesenchymal-epithelial transition25 ."

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BAP1 activates SNAI1. 2 / 2

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