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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

USP7 deubiquitinates FOXO. 3 / 3

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"This process may be reversed by the deubiquitination of FOXO proteins mediated by HAUSP and USP7."

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"Deubiquitination of FOXO requires the deubiquitinating enzyme USP7 and HAUSP (herpesvirus associated ubiquitin specific protease), which interacts with and deubiquitinates FOXO in response to oxidative stress."

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"Deubiquitination of Foxo is mediated by the deubiquitinating enzyme USP7."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

USP7 deubiquitinates FOXO. 3 / 3

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