IndraLab

Statements


3 | 2

sparser
"Viral infection leads to the IRF3/7-dependent upregulation of OTUD4 which interacts with MAVS to remove K48-linked polyubiquitin chains, thereby maintaining MAVS stability and promoting innate antiviral signaling."

No evidence text available

No evidence text available

No evidence text available

sparser
"Viral infection causes the IRF3/7-dependent induction of OTUD4, which binds to MAVS to cleave K48-conjugated ubiquitin chains, stabilizing MAVS and activating antiviral innate immune responses [ xref ]."