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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Lipoxygenase activates KCNMA1. 2 / 2

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"Endogenous chemicals such as arachidonic acid and the metabolites of cytochrome P450, epoxygenase and lipoxygenase, have been found to increase BK channel activity and be important regulators of vascular tone."

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"Thus, lipoxygenase metabolites of arachidonic acid stimulate BK channel activity in GH cells through a calcium independent mechanism involving a protein phosphatase."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...