IndraLab

Statements

BRAF phosphorylated on S446 is kinase-active. 2 / 2

2 |

"78,136,143 The homologous site on B-Raf, S445, is constitutively phosphorylated, accounting for the higher basal activity of B-Raf."

16170185

➶

bel

"The homologous site on B-Raf, S445, is constitutively phosphorylated, accounting for the higher basal activity of B-Raf. Ras presumably phosphorylates this site by activating PI3K."

16170185

INDRA sources:

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IndraLab

Statements

BRAF phosphorylated on S446 is kinase-active. 2 / 2

INDRA sources:

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