IndraLab

Statements



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"Restoration of UCHL1 inhibited the migration and invasion of NPC cells in vitro and in vivo, and knockdown of UCHL1 promoted NPC cell migration and invasion in vitro and in vivo."

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"UCHL1 downregulation decreases the proliferation, migration, and invasion of lung adenocarcinoma cells (40)."

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"Furthermore, the expression of UCHL1 has been demonstrated to be dysregulated in several tumor types, including pancreatic, colorectal and breast cancers, where it can enhance cancer invasion and metastasis (117,118)."

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"In addition, restoration of UCHL1 inhibits tumor invasion and metastasis in vitro and in vivo."

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"Further studies demonstrated that the overexpression of UCHL1 reversed the suppressive effects on cellular viability, proliferation, and invasion of MTC cells caused by ZFAS1 silencing (Figure 5C–E)."

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"As shown in Figure XREF_FIG, B16F10 cells overexpressing UCH-L1 showed increased ability for invasion, while knocking-down UCH-L1 decreased their invasiveness."

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"Migration and invasion of SCNEC tumor cells were induced by UCHL1 over-expression and suppressed by UCHL1 down-regulation, as shown by scratch and transwell invasion assays."