IndraLab

Statements


USP8 is phosphorylated on S718. 15 / 15
7 | 6 2

sparser
"We therefore examined whether UBPY undergoes phosphorylation at Ser 680 ."

No evidence text available

sparser
"As with Usp8 phosphorylation of S680, serine phosphorylation of USP16 and USP44 plays a role during mitosis [35,63,64] ."

No evidence text available

sparser
"This phosphorylation of USP8 at S680 permits complex formation with 14-3-3 proteins ."

rlimsp
"Metabolic labeling with [(32)P]orthophosphate and immunoblotting using antibody against the phosphorylated 14-3-3-binding motif showed that Ser(680) is a major phosphorylation site in UBPY."

No evidence text available

No evidence text available

No evidence text available

sparser
"In the interphase stage of cell division, the Ser680 residue of USP8 is phosphorylated, which enables USP8 to bind to the 14-3-3 protein This binding in turn inhibits the catalytic activity of USP8 ( xref ) ( xref )."

No evidence text available

sparser
"Phosphorylation of the deubiquitinating enzyme USP8 at serine 680 was found essential for its interaction with 14-3-3epsilon and for maintaining USP8 in the cytosol."

rlimsp
"The phosphorylation of USP8 on the fourth serine (S718) of its 14-3-3 binding motif results in its binding with 14-3-3 proteins and catalytic inactivation."

sparser
"The study found that phosphorylation of USP8 at serine 680 was essential for its interaction with 14-3-3epsilon and for retaining/stabilizing USP8 in the cytosol [ xref ]."

No evidence text available