IndraLab

Statements

CYLD activates TNF. 9 / 13
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"CYLD Limits Gene Activation and Enhances Cell Death in Response to TNF."
26670046
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"CYLD Promotes TNF-"
27738385
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"Moreover, overexpression of CYLD increased TNF-alpha induced cell apoptosis in A549 cells."
27738385
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"CYLD deficient cells are protected from RIPK1 mediated necroptosis in response to TNF plus caspase inhibition with or without Smac mimetic."
25459879
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"Consistent with a role in programmed necrosis, CYLD promotes the assembly of the RIP1-FADD-caspase 8 complex in response to TNF, IAP antagonist, and zVAD-fmk treatment [XREF_BIBR]."
20346680
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"Hence, the deubiquitinase function of CYLD is required to promote TNF induced programmed necrosis."
24098568
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"CYLD induction mediated, at least in part, the TZD mediated downregulation of tumor necrosis factor alpha (TNFalpha)-induced interleukin 8 (IL-8)."
27865894
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"In addition, CD11c-Cre Cyld (ex7/8 fl/fl) DCs produced more TNF, IL-10, and IL-12 upon infection, which led to enhanced stimulation of IFN-gamma-producing NK cells."
25675948
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"RNAi mediated silencing of CYLD attenuates ROS production and TNF induced programmed necrosis [XREF_BIBR]."
24098568