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Lithium chloride inhibits JUN. 2 / 2

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"As shown in Figure 2 D, both Kenpaullone and LiCl partially prevented the decrease in endogenous c-Jun levels due to PD98059, confirming that GSK3 mediates the effects of ERK on c-Jun."

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"To confirm the mechanisms responsible for the GSK-3beta-dependent degradation of c-Jun, control shRNA and CD44 shRNA cells were treated with lithium chloride (LiCl), which inhibits GSK-3beta activity."

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IndraLab

Statements

Lithium chloride inhibits JUN. 2 / 2

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