IndraLab

Statements

NPTN binds FGFR1. 6 / 6
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sparser
"Furthermore, we identify a sequence motif in the Ig2 module of Np55 interacting with FGFR1 and show that a synthetic peptide encompassing this motif, termed narpin, binds to and activates FGFR1."
19952283
sparser
"A peptide derived from the Np55-FGFR1 binding site, narpin, might represent an attractive pharmacological tool for the treatment of mental disorders ( Owczarek et al., 2010 )."
22036663
sparser
"Furthermore, a peptide derived from the Np55-FGFR1 binding site has antidepressant-like effects in an animal model of depression ( Owczarek et al., 2010 ; discussed in detail in the next chapter)."
22036663
reach
"Recently, it was demonstrated that neuroplastin binds to and activates fibroblast growth factor receptor 1 (FGFR1) XREF_BIBR, and it may have a function in FGF signaling in OBNSC and hESCs."
22485144
reach
"Recently, it was demonstrated that neuroplastin binds to and activates fibroblast growth factor receptor 1 (FGFR1) XREF_BIBR, and it may have a function in FGF signaling in hESCs."
21829537
reach
"The binding between Np65 and FGFR1 most likely occurs via the Ig2 module of Np65."
22036663