IndraLab

Statements


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"TNF-alpha-induced nuclear NF-kappaB p65 accumulation (XREF_FIG) was significantly suppressed by HMC05 and berberine (XREF_FIG)."

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"Another study found that the treatment of berberine reduced the activity of NF-κB-related transcription factors p50, p52, p65, c-Rel and RelB in the hippocampus of APP/PS1 mice and increased the activity of IκB protein, thereby inhibiting the activation of the NF-κB pathway and reducing neuroinflammation [96]."

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"Downregulation of p65 by Berberine In Vitro."

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"Immunofluorescence staining demonstrated that NF-kappaB p65 was suppressed by berberine in HepG2 cells (XREF_FIG)."

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"The results showed that berberine hydrochloride obviously inhibited the activation of NF-κB p65 subunit and the degradation of IκBα in the LPS-induced mouse endometritis model."