IndraLab

Statements


MiR-129-5p decreases the amount of MYSM1. 2 / 2
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"When overexpressed in astrocytes, miR-129-5p significantly suppressed Mysm1 expression, promoted phosphorylation of p53 and AMPK, and enhanced the expression of PGC1alpha, factors previously associated with ATP production."

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"Interestingly, miR-129-5p overexpression also effectively decreased Mysm1 levels in depressive mice.In addition, Chang et al. identified MAPK1 as a direct target of miR-129-5p [58]."