IndraLab

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OTULIN deubiquitinates RIPK1. 2 / 2

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"OTULIN reduced ubiquitination of both, caspase-8 and RIPK1, identifying RIPK1 and caspase-8 as linearly ubiquitinated proteins (Fig XREF_FIG A)."

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"We found that Otulin deficiency led to the excessive linear ubiquitination of RIPK1 and subsequent NF-κB activation ( Figures 2 B–2D), which is consistent with previous findings ( Gerlach et al., 2011[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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IndraLab

Statements

OTULIN deubiquitinates RIPK1. 2 / 2

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