IndraLab

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USP29 activates SNAI1. 6 / 6
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"18 In addition, USP29 was reported to promote gastric cancer cell migration by cooperating with phosphatase SCP1 to stabilize Snail protein."
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"USP29 enhances chemotherapy-induced stemness in non-small cell lung cancer via stabilizing Snail1 in response to oxidative stress."
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"Deubiquitinase USP29 promotes cell migration by stabilizing Snail protein ."
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"Deubiquitinase USP29 promotes gastric cancer cell migration by cooperating with phosphatase SCP1 to stabilize Snail protein."
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"For example, USP3, USP11, and USP29 stimulate EMT in glioblastoma cells, as well as in ovarian or gastric cancer cells, respectively, by stabilizing Snail [80–82] ."
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"In addition, USP29 overexpression induced by chemotherapy and oxidative stress treatment can promote chemotherapy resistance by hijacking the USP29/Snail1 axis, which is associated with enhanced cancer stem cell properties, poor prognosis and drug resistance in lung cancer (91)."
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