IndraLab

Statements

USP9X decreases the amount of YAP1. 3 / 3
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"Depletion of USP9X in ovarian cancer cell line OVCAR8 also downregulated YAP1 protein levels (XREF_SUPPLEMENTARY)."
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"Similarly, depletion of USP9X in cells using two specific shRNAs significantly decreased YAP1 protein levels (XREF_FIG) and increased cellular sensitivity to MMC, cisplatin and etoposide (XREF_FIG), while reconstituting USP9X depleted cells with FLAG-YAP1 reversed chemotherapy drugs hypersensitivity (XREF_FIG)."
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"Concersely, depletion of USP9X in MDA-MB-231 cells significantly decreased YAP1 protein level but did not affect YAP1 mRNA level (XREF_FIG)."
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