IndraLab

Statements

CYLD inhibits TNF. 4 / 10
| 4
reach
"OPTN is required for CYLD dependent deubiquitination of RIP and also for CYLD dependent inhibition of TNFalpha induced by NF-kappaB activity."
29951055
reach
"The tumor suppressor cylindromatosis (CYLD) inhibits the NF-kappaB pathway by deubiquinating the IKKgamma subunit, as well as TNF receptor associated factor (TRAF) 2, TRAF6, and B-Cell CLL and Lymphoma 3 (BCL3) that are required for maintaining NF-kB activity."
27422962
reach
"CYLD can limit TNF induced prosurvival signaling and promote cell death [XREF_BIBR - XREF_BIBR]."
33432113
reach
"Concomitant Loss of OTULIN and CYLD Interaction with HOIP Increases M1Ubiquitination at the TNF-RSC and Enhances TNF Induced Gene Activation."
26670046