IndraLab

Statements

EBNA1 activates USP7. 3 / 3
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"We show that EBNA1 also increases the occupancy of USP7 at PML NBs and that CK2 and USP7 bind independently and simultaneously to EBNA1 to form a ternary complex."
20719947
reach
"USP7 and HAUSP is a key regulator of p53 and Mdm2 and is targeted by the Epstein-Barr nuclear antigen 1 (EBNA1) protein of Epstein-Barr virus (EBV)."
15808506
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"This anti-apoptotic activity may be mediated by the ability of EBNA-1 to sequester the deubiquitinating enzyme HAUSP/USP7 that regulates the turnover of p53 [34,35] ."
19619655