IndraLab

Statements

ATP activates KCNMA1. 13 / 13
| 13
reach
"The most prominent current component during ATP stimulation in hslo expressing cells was conducted BK (Ca) which resulted in a pronounced transient hyperpolarization."
9502199
reach
"Interestingly, while there was a trend toward a higher percentage of cells responding to ATP stimulation in the SLO condition (Figure 5c), SLO-treated cells depicted slower calcium dynamics, with longer decay time (Figure 5e), delayed peak time (Figure 5f), and increased AUC (Figure 5h) compared to control cells, while peak amplitude remained similar (Figure 5g)."
40041406
reach
"This exogenous ATP then can lead to BK channel activation in the Vero cells and Muller glial cells [56,57] via its binding to purinergic receptors."
27359377
reach
"In conclusion, our results indicate that PACAP causes cerebellar artery dilation through two mechanisms : 1) K ATP channel activation and 2) enhanced BK channel activity, likely through increased Ca 2+ spark frequency."
24744252
reach
"A number of ATP-activated K and Ca -activated K (BK or maxi-K and SK) channel openers have demonstrated that activation of potassium channels can reduce the spontaneous or stimulus-induced contractions of isolated bladder strips [110]."
27713353
reach
"SLO alone inhibited Akt and Foxo1 phosphorylation; by contrast ATP supplementation together with SLO enhanced Akt-Foxo1 signaling and corrected the defects associated with LDHA deficiency (Fig. 3C and fig."
33479154
reach
"The most prominent current componentduring ATP stimulation in hslo expressing cells was conducted BK,, which resulted in a pronouncedtransient hyperpolarization.This hyperpolarization, which was absen[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
9502199
reach
"In cell attached recordings, ATP activated a 230-pS BK channel."
8944628
reach
"Potential molecular targets include the K ATP channel ( Lu et al., 2002 ) and the calcium-activated BK channel (BK Ca ) ( Campbell et al., 1996; Li and Campbell, 1997 )."
28526610
reach
"Inclusion of SLO in T cell culture diminished PIP3 generation, whereas ATP supplementation together with SLO enhanced PIP3 production in both Ldha and Cd4 Ldha T cells (Figures 7A and S7A)."
33979589
reach
"BK channel open probability (Po) of all cells lines used was increased by H 2 S in ATP containing solutions."
25429270
reach
"Thus, at positive membrane potential, the activation of the BK channel caused by ATP was sufficient to counterbalance the inhibition of the BK channel caused by the chelation of free calcium by ATP; at negative membrane potential, however, the effect of ATP on P open was more inhibitory than would be expected, even bearing in mind the chelation of free calcium by ATP."
23284908
reach
"In the vasculature, the most important K+ channel subclasses that are involved in the action of various endothelium derived relaxing factors are the ATP sensitive KATP channel and the large conductance calcium activated BK channel."
21499479