IndraLab

Statements


Kinase-active AKT1 phosphorylates TSC2 on T1462. 4 / 4
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"Akt then phosphorylates tuberin on three residues (S939, S1130 and T1462 of full length human tuberin), and this inhibits the tuberin-hamartin complex through an as-yet-undefined mechanism (reviewed in [8])."

"Akt then phosphorylates tuberin on three residues (S939, S1130 and T1462 of full length human tuberin), and this inhibits the tuberin-hamartin complex through an as-yet-undefined mechanism (reviewed in [8])."

"Figure 4. S939 and T1462 Are the Major PI3K-Dependent Phosphorylation Sites on Tuberin"

"Figure 4. S939 and T1462 Are the Major PI3K-Dependent Phosphorylation Sites on Tuberin"