IndraLab

Statements

MTORC2 activates KCNMA1. 4 / 4
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"However, the dual inhibitor of mTORC1 and mTORC2 AZD8055 and short hairpin RNA targeting Rictor downregulated BK channel mRNA and protein levels and bioactivity."
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"In summary, our study demonstrated that inhibition of mTORC2 downregulates BK channel mRNA and protein levels and functions in podocytes."
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"These data indicate mTORC2 mediated BK channel activity by influencing the surface expression of BK channels through Akt."
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"Inhibition of mTORC2 Decreases BK Channel mRNA and Protein Levels in Podocytes."
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