IndraLab

Statements

USP47 activates SNAI1. 3 / 3
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"Because hypoxia induced USP47 expression enhanced EMT by stabilizing Snail, we investigated the contribution of USP47 to tumor growth and invasion in vivo."
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"Silencing of USP47 accelerated the proteasomal degradation of Snail and inhibited EMT."
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"Additionally, chemical inhibition of USP47 reduced the expressions of several EMT markers, including CDH1, CTNNB1, and SNAIL, and reversed the morphological changes in MCF-10A cells undergoing EMT (Silvestrini et al., 2020)."
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