IndraLab

Statements

USP18 decreases the amount of ISG15. 3 / 3
| 3
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reach
"As expected, incubation with purified USP18 decreased ISG15 conjugates and increased levels of free ISG15 [88]."
35159348
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reach
"We demonstrated that USP18 deficient cells have increased expression of IFIT1, IFIT2, IFIT3, IFITM1, IFITM2, CXCL9, CXCL10, ISG15, and MX2 after treatment with exogenous IFN-. Many of these genes have been previously shown to restrict HIV-1 replication."
29437254
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reach
"We demonstrated that USP18 deficient cells have increased expression of IFIT1, IFIT2, IFIT3, IFITM1, IFITM2, CXCL9, CXCL10, ISG15, and MX2 after treatment with exogenous IFN‐β."
29437254