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USP3 activates EPHA2. 2 / 2

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"In additional, we also found that overexpression of USP3 led to a decrease in the ubiquitination level of EPHA2 protein (Fig. 5A), whereas knockdown of USP3 promoted degradation of EPHA2 through ubiquitination (Fig. 5B)."

38531846

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"Mechanistically, USP3 activated PI3K/AKT signaling pathway through binding to EPHA2 and then reducing its protein degradation."

38531846

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IndraLab

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USP3 activates EPHA2. 2 / 2

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