IndraLab

Statements


MiR-3191-5p inhibits CACNA1A. 4 / 4
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"MiR-3191-5p inhibits the translational initiation of CACNA1A IRES driven alpha1ACT by eIF4AII and eIF4GII."

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"These results suggest that miR-3191-5p interacts with CACNA1A IRES only through its predicted binding site and inhibits the CACNA1A IRES driven translation of alpha1ACT while sparing alpha1A expression and CACNA1A mRNA expression."

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"MiR-3191-5p inhibits the CACNA1A IRES driven translation of alpha1ACT while sparing alpha1A and CACNA1A mRNA expression."

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"Dual-luciferase assays revealed that miR-711, miR-3191-5p, and miR-4786-3p down-regulated CACNA1A IRES driven luciferase activities compared to a negative control miRNA (XREF_FIG)."