IndraLab

Statements

USP9X activates HYCC1. 5 / 5
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"USP9X enhances proliferation of HCC cells and is correlated with undesirable prognosis."
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"18 , 19 , 20 Conversely, deubiquitinase USP10 and USP9X stabilize YAP and promote cell growth and survival in HCC and breast cancer."
39968498
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"Furthermore, two deubiquitinating enzymes, USP9X and USP28, have significant expression in HCC and could similarly promote HCC cell proliferation by regulating the activity of this pathway (128, 129)."
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"By contrast, USP9X depletion causes significant proliferation inhibition in HCC cells."
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"It was also clarified that aberrant fatty acid metabolism (FAM) might accelerate tumor growth and metastasis of HCC."
36881382