IndraLab

Statements

Modified USP25 leads to the deubiquitination of DDX58. 5 / 5
| 5
reach
"We observed that overexpression of USP25 significantly inhibited ubiquitination of RIG-I (XREF_FIG), TRAF2 (XREF_FIG), and TRAF6 (XREF_FIG)."
24260525
reach
"We observed that overexpression of USP25 significantly inhibited ubiquitination of RIG-I (Figure 7B), TRAF2 (Figure 7D), and TRAF6 (Figure 7E)."
24260525
reach
"Overexpression of USP21 inhibited RNA virus induced RIG-I polyubiquitination and RIG-I-mediated interferon (IFN) signaling, whereas deletion of USP21 resulted in elevated RIG-I polyubiquitination, IRF3 phosphorylation, IFN-alpha and beta production, and antiviral responses in MEFs in response to RNA virus infection."
24493797
reach
"We observed that overexpression of USP25 significantly inhibited ubiquitination of RIG-I (Figure Figure 7E )."
24260525
reach
"We further examined the role of USP21 in the inhibition of SeV induced RIG-I polyubiquitination and found that overexpression of USP21 WT but not C221A mutant inhibited SeV induced polyubiquitination of both FLAG tagged and endogenous RIG-I (XREF_FIG)."
24493797