IndraLab

Statements


TNFAIP3 decreases the amount of TNF. 4 / 5
1 | 4

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"TNFAIP3 inhibits the secretion of TNFa in the TNF-signaling pathway, which, in turn, affects the downstream pathway of the TNF signaling pathway to regulate adipocyte differentiation [32,33]."

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"TNFAIP3 knockdown enhanced TNF expression in the presence of TNF, TNF plus budesonide, and TNF plus budesonide-formoterol combination and confirms feedback inhibition."

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"The finding does not preclude the observation increased TNF-α signaling in the bloodstream of severe patients [33] , as TNFAIP3 depletion has been shown to cause increased TNF-α expression [56] ."
| DOI

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"79 Chen et al. 24 found that TNFAIP3 inhibited the mTOR signalling pathway to promote autophagy, reduce the expression of TNF‐α and IL‐1β, and inhibit ECM degeneration in human NP cells."