IndraLab

Statements

Apigenin inhibits MYD88. 5 / 5
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"Apigenin in LPS-exposed macrophages reduces TLR-4 , MyD88 and phosphorylation of IkappaKB levels through nuclear NF-kappaB p65 signaling pathway [ 192 ] ."
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"In vitro functional studies showed that Apigenin decreased LPS and IFN-gamma-induced microglial inflammatory factor production and M1-activation via the TLR4/MyD88 pathway."
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"Apigenin could decrease MyD88, p-IκB-α, and NF-κB p65 which indicates its protective effects against inflammation and atherosclerotic plaque formation."
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"Apigenin Attenuated Microglia Inflammation Via TLR4/MyD88 Signaling Pathway."
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"We also found that Apigenin significantly blocked the TLR4/MyD88 pathway, a pathway that was seen in EAU and microglial polarization."
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