IndraLab

Statements

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"XREF_BIBR showed that BAP1 overexpression in BAP1-null malignant pleural mesothelioma cell lines promoted cell proliferation and that BAP1 knockdown decreased proliferation in three malignant pleural mesothelioma cell lines."
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"In cutaneous melanoma cell lines, however, stable over-expression of BAP1 promoted cell growth while knockdown of BAP1 suppressed cell proliferation with concomitant decrease of survivin, an anti-apoptotic protein [17]."
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"Our data suggest that BAP1 promotes cell proliferation and migration , and enhances the expression of KLF5 and its downstream genes , including CyclinD1 and FGF-BP1 , in the esophageal carcinoma cell line ECA109 ."
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"In both cell lines, knockdown of BAP1 significantly inhibited cell proliferation (P < 0.05; XREF_FIG and XREF_FIG) and clonogenic survival (XREF_FIG - XREF_FIG)."
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"In conclusion, BAP1 is a KLF5 DUB and BAP1 promotes basal breast cell proliferation, migration, tumour growth and metastasis partially through stabilizing KLF5 (XREF_SUPPLEMENTARY)."
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"BAP1 contributes to colon cancer cell proliferation by accelerating DNA replication and suppressing replication stress and concomitant apoptosis."
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"In summary, despite the findings implicating BAP1 in suppression of proliferation XREF_BIBR, XREF_BIBR, some groups have reported that BAP1 promotes cell proliferation XREF_BIBR, XREF_BIBR, XREF_BIBR."
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"These results confirmed that BAP1 promotes cell proliferation in vitro through KLF5 in part."
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"BAP1 promotes breast cancer cell proliferation and metastasis by deubiquitinating KLF5."
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"Reintroduction of BAP1 into BAP1 deficient mesothelioma cells either had no effect or modestly increased cell proliferation."
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"BAP1-Related ceRNA (NEAT1/miR-10a-5p/SERPINE1) Promotes Proliferation and Migration of Kidney Cancer Cells."
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"Studies of the effects of BAP1 on cell proliferation have shown conflicting results, with some reporting that BAP1 suppresses cell proliferation, and others reporting that BAP1 enhances proliferation."
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"In agreement with previous work in other cell types [XREF_BIBR, XREF_BIBR, XREF_BIBR], transient BAP1 loss decreased cell proliferation."
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"These results indicate that BAP1 promotes KLF5 positive breast cell proliferation in vitro."
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"Taken together, these data revealed that downregulation of BAP1 promotes proliferation, G1 to S cell cycle progression, and invasion of ICC in vitro."
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"In both cell lines , knockdown of BAP1 significantly inhibited cell proliferation ( P < 0.05 ; Fig. 1A and B ) and clonogenic survival ( Fig. 1C-F ) ."
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"BAP1 promotes breast cancer cell proliferation and migration in vitro and tumour growth and lung metastasis in vivo."
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"BAP1 promotes cell proliferation through KLF5."
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"42 Kruppel like factor 5 (KLF5) is stabilized by the DUB BRCA1 associated Protein 1 (BAP1), promoting breast cancer cell proliferation."
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"Similarly, Qin et al. showed that knockdown of BAP1 in several breast cancer cell lines inhibited cell proliferation, tumorigenicity and metastasis."
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"BAP1 deficiency may enhance cellular proliferation as well as lipid synthesis."
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"Here, we show that BAP1 is upregulated in colon cancer cells and tissues and that BAP1 depletion reduces colon cancer cell proliferation and tumor growth."
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"MTT, cell scratch and transwell migration assays showed that low expression of BAP1 significantly promoted the proliferation and migration of UVM cells."
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"BAP1 interacts with Krüppel-like factor 5 (KLF5) to stabilize KLF5 and promotes proliferation of breast cancer cells42."
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"BAP1 promotes proliferation in HNSCC cells regardless of HPV status."
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"Downregulation of BAP1 promotes proliferation, cell cycle progression, and invasion of ICC in vitro."
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