IndraLab

Statements


BAP1 inhibits FOXK2. 3 / 3
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"Moreover, BAP1 is part of a ternary complex bridging FOXK2 and HCF1 and represses FOXK2 target genes, an effect requiring BAP1 DUB activity but not the interaction with HCF1 binding."

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"BAP1 represses FoxK2 target genes, and this effect requires BAP1 DUB activity but not interaction with HCF-1."

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"Loss of BAP1 causes the increase of FoxK2 target genes, which is dependent on the Ring1B and Bmi1 complex."