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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

BAP1 inhibits FOXK2. 3 / 3

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"Moreover, BAP1 is part of a ternary complex bridging FOXK2 and HCF1 and represses FOXK2 target genes, an effect requiring BAP1 DUB activity but not the interaction with HCF1 binding."

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"BAP1 represses FoxK2 target genes, and this effect requires BAP1 DUB activity but not interaction with HCF-1."

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"Loss of BAP1 causes the increase of FoxK2 target genes, which is dependent on the Ring1B and Bmi1 complex."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

BAP1 inhibits FOXK2. 3 / 3

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