IndraLab

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USP8 inhibits SAIT301. 3 / 3

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"Interestingly, the USP8 was reported to deubiquitinate LRIG1 and reverse the SAIT301 activity and thus decrease LRIG1 and MET degradation."

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"Over-expression of USP8 almost completely reversed SAIT301 induced growth inhibition of EBC1 cells."

24828152

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"Over-expression of USP8 significantly reversed SAIT301 mediated degradation of both LRIG1 and Met while USP8-CS had no such impact (XREF_FIG)."

24828152

INDRA sources:

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IndraLab

Statements

USP8 inhibits SAIT301. 3 / 3

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