IndraLab

Statements

USP8 binds LRIG1. 11 / 11
1 | 5 5
reach
"Collectively, these results suggest that SAIT301 triggers degradation of LRIG1 by interfering the interaction of USP8 and LRIG1, and USP8 regulates ubiquitin modification and stability of LRIG1."
24828152
reach
"Interestingly, SAIT301 treatment markedly decreased the interaction of LRIG1 and USP8 (XREF_FIG)."
24828152
sparser
"Interestingly, SAIT301 triggers LRIG1/Met degradation by interfering with LRIG1-USP8 interaction."
25183430
reach
"SAIT301 triggers degradation of LRIG1 by inhibiting the interaction of LRIG1 and USP8, which regulates ubiquitin modification and stability of LRIG1."
24828152
sparser
"We also identified USP8 as a LRIG1-specific deubiquitinating enzyme, reporting the interaction between USP8 and LRIG1 for the first time."
24828152
sparser
"Collectively, these results suggest that SAIT301 triggers degradation of LRIG1 by interfering the interaction of USP8 and LRIG1, and USP8 regulates ubiquitin modification and stability of LRIG1."
24828152
sparser
"We demonstrated that SAIT301 inhibits the interaction of LRIG1 and USP8."
24828152
reach
"We also identified USP8 as a LRIG1 specific deubiquitinating enzyme, reporting the interaction between USP8 and LRIG1 for the first time."
24828152
sparser
"Interestingly, SAIT301 treatment markedly decreased the interaction of LRIG1 and USP8 ( xref )."
24828152
biogrid
No evidence text available
24828152
reach
"We demonstrated that SAIT301 inhibits the interaction of LRIG1 and USP8."
24828152